Scientists at the Buck Institute for Research on Aging in Novato are advocating for research to determine whether eating fatty foods could be protective for the coronavirus. Ketone bodies are compounds produced naturally during fat metabolism. Eating a ketogenic diet, which is high in fat and low in carbohydrates, accelerates the production of the primary ketone beta-hydroxybutyrate acid BHB. Small clinical trials in humans have demonstrated that BHB can improve cardiac function in people with heart failure. In the laboratory setting, BHB has also shown promise in treating type 2 diabetes and reducing harmful inflammation. Elevation of blood ketones have proved to be protective against tissue damage due to a lack of oxygen, which occurs in severe respiratory infections. The hope is that the diet will reduce the systemic inflammation, known as a cytokine storm, that results in acute respiratory distress syndrome. Noting the false claims for hydroxychloroquine made by President Trump, Newman is quick to acknowledge that there is no evidence that a ketogenic diet is protective in any way against COVID In fact, he says there might be instances where BHB could promote viral replication of coronavirus. Ketone bodies and the coronavirus both bind to some of the same proteins. Newman said while a ketogenic diet is effective in addressing two major risks for heart disease, obesity and diabetes, many cardiologists still want to see more long-term study before endorsing its safety.
For their newly reported study, the UCSF-led team partnered with the nonprofit Nutrition Science Initiative to recruit 17 adult overweight or obese nondiabetic men to spend two months as inpatients in a metabolic ward where their diets and exercise levels were carefully monitored and controlled. University of California. In fact, he says there might be instances where BHB could promote viral replication of coronavirus. Eating a ketogenic diet, which is high in fat and low in carbohydrates, accelerates the production of the primary ketone beta-hydroxybutyrate acid BHB. They quickly organized testing for marginalized communities around the Bay Area and the nation, rapidly built a state-of-the-art diagnostic laboratory within days, and partnered with the state to train thousands of contact tracers. The hope is that the diet will reduce the systemic inflammation, known as a cytokine storm, that results in acute respiratory distress syndrome. All Supplement. He says that various strategies exist for reducing the risk for heart disease, such as lowering blood pressure and cholesterol levels. The chancellor also highlighted work from researchers who are studying the genomes of COVID patients, mapping out the immune response, searching for the cellular proteins targeted by the new virus, and developing inhalable technologies to prevent infection.
That fat is turned into ketone bodies, which are an alternative energy source: besides glucose derived from carbohydrates, ketones from fat are the only fuel the brain can use. The high-fat, low-carbohydrate regimen of ketogenic diets changes the way the body uses energy. A New Cancer-Killing Fungus. UC San Diego. San Francisco Chronicle. These benefits are less well-established in humans, however, in part because of the difficulty in maintaining a ketogenic state.